Lynchburg Back Pain Related to Inflammation Reduced with Melatonin

Inflammation. Disc Degeneration. There is a connection. Inflammation acts as the body’s response system to damaging stimuli (injury, pathogens, metabolic stress – a disc herniation pushing on a nerve!) as it attempts to repair itself before the harm was achieved. Palmer Chiropractic Center is always amazed at what the body can do! Palmer Chiropractic Center sees its Lynchburg chiropractic care as the body’s partner in healing especially when spine pain is an issue. Chiropractic care uses many tools like spinal manipulation, exercise, and nutrition to take care of the body. Melatonin is one nutritional tool that is proving value in its ability to interrupt the inflammatory process related disc herniation that brings about pain relief: back, neck, spine-related.

DISC DEGENERATION AND INFLAMMATION AND 'AUTOPHAGY'

Inflammatory markers interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are related to intervertebral disc degeneration. (1) IL-1 β in fact promotes itself, its own expression, by upregulating NLRP3 inflammasome activation. (2) The body controls itself down to its cellular level via autophagy, the natural process via which the body’s cells clear out damaged (ie, by inflammation) or unneeded parts. In a recent study, melatonin boosted autophagy and reduced the degradation of the disc’s extracellular matrix (technically indicated by a decline in marker LC3B, autophagasomes and autolysosomes and inhibition of the NF-kB signaling pathway). The end conclusion was that melatonin prevents intervertebral disc degeneration by promoting autophagy. (3) Wow. Palmer Chiropractic Center is inspired by this research to see just how well melatonin can perform for Lynchburg back pain related to disc degeneration.

MELATONIN AND ITS HEALING WAYS FOR THE DISC

Disc degeneration is a very common malady seen at Palmer Chiropractic Center that positive news of melatonin’s benefits are quite rousing. A new study stated that melatonin could modify the extracellular matrix of the disc remodeling process started by IL-1 β. Additionally, melatonin reduced the inflammatory cell collection and reduced the release of connected inflammatory markers IL-1β, IL-6, and TNF-α. With this new discovery that melatonin disrupted the IL-1B feedback loop, researchers suggested that melatonin may support the restoration process of intervertebral discs after damage was already present. (1) Palmer Chiropractic Center continues following the new research on the role inflammation performs in Lynchburg disc degeneration and melatonin’s role in reducing it.

INFLAMMATION AND MELATONIN

The importance of melatonin in assisting to slow or stop painful conditions due to inflammation is rising. The description of melatonin as a multitasking molecule affecting mood, immunity, and energy among other things is quite fitting. It is also anti-oxidant, anti-aging, and anti-inflammatory, specifically by blocking the activation of inflammasomes (4) Melatonin’s formal chemical name is as about as long as its list of tasks: N-acetyl-5-methoxytryptamine. The pineal gland secretes melatonin naturally. Melatonin impacts the body’s aging, anti-inflammatory, anti-apoptosis (cell death), and autophagy (cell-cleanout) processes. (1) Melatonin’s specific influence on inflammation and disc degeneration is most interesting to Palmer Chiropractic Center and our Lynchburg back pain patients.

CONTACT Palmer Chiropractic Center

Listen to this PODCAST with Dr. Hrefna Sylvia based in Iceland where back pain isn’t much different from any other country on The Back Doctors Podcast with Dr. Michael Johnson as she describes how The Cox® Technic System of Spinal Pain Management handles disc degeneration for relief of chronic low back pain in her patient.

Schedule your Lynchburg chiropractic appointment with Palmer Chiropractic Center soon. We can discuss the role inflammation plays in your back pain experience and how melatonin may address the related disc degeneration.

 
Palmer Chiropractic Center presents new findings that melatonin interrupts the inflammatory process in disc degeneration that causes back pain. 
 
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